GATE 2024 Syllabus for Biotechnology (BT): Download PDF and Print

GATE 2024 Syllabus for Biotechnology (BT). IISc Bangalore, the exam authority released GATE syllabus for BT along with the official brochure download in PDF.

GATE Syllabus 2024 for BT Paper: The Indian Institute of Science (gate.iisc.ac.in), Bangalore, the organising institute officially released complete syllabus of Biotechnology (BT) Paper for GATE 2024 exams.

The syllabus of paper BT (Biotechnology) has been divided into seven sections. The corresponding sections of the question paper contain different topics.

You may download GATE admit card and GATE exam schedule for paper Biotechnology for appearing in the Graduate Aptitude Test in Engineering for the year 2024.

GATE 2024 Paper Pattern for Biotechnology:

PaperBiotechnology
Paper CodeBT
Examination ModeComputer Based Test (CBT)
Duration3 Hours (180 Minutes)
Type of Questions(a) Multiple Choice Questions (MCQ)
(b) Multiple Select Questions (MSQ) and/or Numerical Answer Type (NAT) Questions
Marking SchemeQuestions carry 1 mark and 2 marks
Negative MarkingFor a wrong answer chosen in a MCQ, there will be negative marking.

For 1-mark MCQ: 1/3 mark will be deducted for a wrong answer.
For 2-mark MCQ: 2/3 mark will be deducted for a wrong answer.

NO negative marking for MSQ & NAT.
Number of Questions10 (GA) + 55 (subject) = 65 Questions
General Aptitude (GA) Marks15 Marks
Subject Marks85 Marks
Total Marks100 Marks
BT Paper Pattern GATE 2024

Section-1 Engineering Mathematics

TopicsGATE 2024 Syllabus of Engineering Mathematics
Linear AlgebraMatrices and determinants; Systems of linear equations; Eigen values and Eigen vectors.
CalculusLimits, continuity and differentiability; Partial derivatives, maxima and minima; Sequences and series; Test for convergence
Differential EquationsLinear and nonlinear first order ODEs, higher order ODEs with constant coefficients; Cauchy’s and Euler’s equations; Laplace transforms.
Probability and Statistics:Mean, median, mode and standard deviation; Random variables; Poisson, normal and binomial distributions; Correlation and regression analysis.
Numerical MethodsSolution of linear and nonlinear algebraic equations; Integration by trapezoidal and Simpson’s rule; Single step method for differential equations.
GATE Syllabus for Engineering Mathematics

Section-2 General Biology

TopicsGATE 2024 Syllabus of General Biology
BiochemistryBiomolecules – structure and function; Biological membranes – structure, membrane channels and pumps, molecular motors, action potential and transport processes; Basic concepts and regulation of metabolism of carbohydrates, lipids, amino acids and nucleic acids; Photosynthesis, respiration and electron transport chain. Enzymes – Classification, catalytic and regulatory strategies; Enzyme kinetics – Michaelis-Menten equation; Enzyme inhibition – competitive, non-competitive and uncompetitive inhibition.
MicrobiologyBacterial classification and diversity; Microbial Ecology – microbes in marine, freshwater and terrestrial ecosystems; Microbial interactions; Viruses – structure and classification; Methods in microbiology; Microbial growth and nutrition; Nitrogen fixation; Microbial diseases and host-pathogen interactions; Antibiotics and antimicrobial resistance.
ImmunologyInnate and adaptive immunity, humoral and cell mediated immunity; Antibody structure and function; Molecular basis of antibody diversity; T cell and B cell development; Antigen-antibody reaction; Complement; Primary and secondary lymphoid organs; Major histocompatibility complex (MHC); Antigen processing and presentation; Polyclonal and monoclonal antibody; Regulation of immune response; Immune tolerance; Hypersensitivity; Autoimmunity; Graft versus host reaction; Immunization and vaccines.
GATE Syllabus for General Biology

Section-3 Genetics, Cellular and Molecular Biology

TopicsGATE 2024 Syllabus of Genetics, Cellular and Molecular Biology
Genetics and Evolutionary BiologyMendelian inheritance; Gene interaction; Complementation; Linkage, recombination and chromosome mapping; Extra chromosomal inheritance; Microbial genetics – transformation, transduction and conjugation; Horizontal gene transfer and transposable elements; Chromosomal variation; Genetic disorders; Population genetics; Epigenetics; Selection and inheritance; Adaptive and neutral evolution; Genetic drift; Species and speciation.
Cell BiologyProkaryotic and eukaryotic cell structure; Cell cycle and cell growth control; Cell-cell communication; Cell signaling and signal transduction; Post-translational modifications; Protein trafficking; Cell death and autophagy; Extra-cellular matrix.
Molecular BiologyMolecular structure of genes and chromosomes; Mutations and mutagenesis; Regulation of gene expression; Nucleic acid – replication, transcription, splicing, translation and their regulatory mechanisms; Non-coding and micro RNA; RNA interference; DNA damage and repair.
GATE Syllabus for Genetics, Cellular and Molecular Biology

Section-4 Fundamentals of Biological Engineering

TopicsGATE 2024 Syllabus of Fundamentals of Biological Engineering
Engineering principles applied to biological systemsMaterial and energy balances for reactive and non-reactive systems; Recycle, bypass and purge processes; Stoichiometry of growth and product formation; Degree of reduction, electron balance, theoretical oxygen demand.
Classical thermodynamics and BioenergeticsLaws of thermodynamics; Solution thermodynamics; Phase equilibria, reaction equilibria; Ligand binding; Membrane potential; Energetics of metabolic pathways, oxidation and reduction reactions.
Transport ProcessesNewtonian and non-Newtonian fluids, fluid flow – laminar and turbulent; Mixing in bioreactors, mixing time; Molecular diffusion and film theory; Oxygen transfer and uptake in bioreactor, kLa and its measurement; Conductive and convective heat transfer, LMTD, overall heat transfer coefficient; Heat exchangers.
GATE Syllabus for Fundamentals of Biological Engineering

Section-5 Bioprocess Engineering and Process Biotechnology

TopicsGATE 2024 Syllabus of Bioprocess Engineering and Process Biotechnology
Bioreaction engineeringRate law, zero and first order kinetics; Ideal reactors – batch, mixed flow and plug flow; Enzyme immobilization, diffusion effects – Thiele modulus, effectiveness factor, Damkoehler number; Kinetics of cell growth, substrate utilization and product formation; Structured and unstructured models; Batch, fed-batch and continuous processes; Microbial and enzyme reactors; Optimization and scale up.
Upstream and Downstream ProcessingMedia formulation and optimization; Sterilization of air and media; Filtration – membrane filtration, ultrafiltration; Centrifugation – high speed and ultra; Cell disruption; Principles of chromatography – ion exchange, gel filtration, hydrophobic interaction, affinity, GC, HPLC and FPLC; Extraction, adsorption and drying.
Instrumentation and Process ControlPressure, temperature and flow measurement devices; Valves; First order and second order systems; Feedback and feed forward control; Types of controllers – proportional, derivative and integral control, tuning of controllers.
GATE Syllabus for Bioprocess Engineering and Process Biotechnology

Section-6 Plant, Animal and Microbial Biotechnology

TopicsGATE 2024 Syllabus of Plant, Animal and Microbial Biotechnology
PlantsTotipotency; Regeneration of plants; Plant growth regulators and elicitors; Tissue culture and cell suspension culture system – methodology, kinetics of growth and nutrient optimization; Production of secondary metabolites; Hairy root culture; Plant products of industrial importance; Artificial seeds; Somaclonal variation; Protoplast, protoplast fusion – somatic hybrid and cybrid; Transgenic plants – direct and indirect methods of gene transfer techniques; Selection marker and reporter gene; Plastid transformation.
AnimalsCulture media composition and growth conditions; Animal cell and tissue preservation; Anchorage and non-anchorage dependent cell culture; Kinetics of cell growth; Micro & macro-carrier culture; Hybridoma technology; Stem cell technology; Animal cloning; Transgenic animals; Knockout and knock-in animals.
MicrobesProduction of biomass and primary/secondary metabolites – Biofuels, bioplastics, industrial enzymes, antibiotics; Large scale production and purification of recombinant proteins and metabolites; Clinical-, food- and industrial- microbiology; Screening strategies for new products.
GATE Syllabus for Plant, Animal and Microbial Biotechnology

Section-7 Recombinant DNA technology and Other Tools in Biotechnology

TopicsGATE 2024 Syllabus of Recombinant DNA technology and Other Tools in Biotechnology
Recombinant DNA technologyRestriction and modification enzymes; Vectors – plasmids, bacteriophage and other viral vectors, cosmids, Ti plasmid, bacterial and yeast artificial chromosomes; Expression vectors; cDNA and genomic DNA library; Gene isolation and cloning, strategies for production of recombinant proteins; Transposons and gene targeting;
Molecular toolsPolymerase chain reaction; DNA/RNA labelling and sequencing; Southern and northern blotting; In-situ hybridization; DNA fingerprinting, RAPD, RFLP; Site-directed mutagenesis; Gene transfer technologies; CRISPR-Cas; Biosensing and biosensors.
Analytical toolsPrinciples of microscopy – light, electron, fluorescent and confocal; Principles of spectroscopy – UV, visible, CD, IR, fluorescence, FT-IR, MS, NMR; Electrophoresis; Micro-arrays; Enzymatic assays; Immunoassays – ELISA, RIA, immunohistochemistry; immunoblotting; Flow cytometry; Whole genome and ChIP sequencing.
Computational toolsBioinformatics resources and search tools; Sequence and structure databases; Sequence analysis – sequence file formats, scoring matrices, alignment, phylogeny; Genomics, proteomics, metabolomics; Gene prediction; Functional annotation; Secondary structure and 3D structure prediction; Knowledge discovery in biochemical databases; Metagenomics; Metabolic engineering and systems biology.
GATE Syllabus for Recombinant DNA technology and Other Tools in Biotechnology

You may download complete GATE syllabus 2024 for BT Biotechnology in PDF. For more detail, please visit official website GATE2024.IISc.ac.in.


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